Superantigen Binding To A T-cell Receptor
by Nanoclustering/science Photo Library
Title
Superantigen Binding To A T-cell Receptor
Artist
Nanoclustering/science Photo Library
Medium
Photograph - Photograph
Description
Superantigen binding to a T-cell receptor, illustration. A superantigen (SAg, pink) is being presented by an antigen-presenting cell (bottom) to a T-cell (top), a type of white blood cell. Superantigens are released by some viruses and bacteria and can generate a strong immune response by inducing huge releases of cytokines in humans. The superantigen binds to the major histocompatibility complex (MHC) class II molecules (blue) of an antigen-presenting cell. This is then presented to a T-cell via a T-cell receptor (TCR, green). This activates the T-cell (non-specific activation), which results in excessive cytokine release.
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May 9th, 2022
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