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Prions in brain disease. Illustration of tangles of malformed proteins (prions, orange) being produced from brain cells at lower left, and binding to neurons (right) inside the brain. Two different mechanisms are shown: smaller tangles (upper centre) and larger balls of strands (lower centre). Prions cause degenerative brain diseases like Creutzfeldt-Jakob disease (CJD). Some theories also ascribe diseases such as Alzheimer's to a form of prion disorder.

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