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Orexin-A hormone molecule. Computer model showing the crystal structure of a molecule of the hormone orexin-A. The crystal structure consists of both the secondary structure, represented by alpha helices (ribbons), and primary structure (rods). Orexin-A is one of a pair of excitatory neuropeptide hormones that regulate the sleep cycle by inducing wakefulness. The other is Orexin-B. Orexins, also known as hypocretins, also play a role in stimulating appetite.

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