Cancer Cell Death Wave Using Carbon Quantum Dots
by Science Photo Library
Title
Cancer Cell Death Wave Using Carbon Quantum Dots
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Science Photo Library
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Photograph - Photograph
Description
Cancer cell death wave using carbon quantum dots. Carbon quantum dots (C dots) are nanoparticles less than 10 nanometers in size. Biomedical researchers are exploring ways to use C dots as drug carriers and fluorescent tags. This image shows cells from a mouse model of melanoma (B16) after treatment with high-dose, melanoma-targeted C dots carrying a therapeutic agent: peptides targeting the melanocortin-1 receptor. After treatment, cancer cells (upper left) die by an iron-driven mechanism called ferroptosis (upper right, green). This results in death spreading through the cells in a wave-like manner. The lower image shows the cell death wave, with individual nuclei pseudocoloured to represent the relative timing of cell death. This image was created in 2017, as part of research carried out at the MSK-Cornell Center for Translation of Cancer Nanomedicine, USA.
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October 8th, 2019
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