Binding Of Taxol To A Tubulin Molecule
by Ramon Andrade 3dciencia/science Photo Library
Title
Binding Of Taxol To A Tubulin Molecule
Artist
Ramon Andrade 3dciencia/science Photo Library
Medium
Photograph - Photograph
Description
Illustration of taxol binding to a tubulin molecule. Tubulin is a dimer consisting of alpha (grey ribbons) and beta (beige ribbons) subunits. Tubulin molecules combine into microtubules forming part of the cytoskeleton. The anti-cancer drug Taxol (white, red and green stick model) stabilises the tubulin when it is bound to guanosine diphosphate (GDP, yellow and red stick model) disrupting the disassembly of microtubules. This action results in chromosomes being unable to achieve a metaphase spindle configuration disrupting the progression of cell division (mitosis). Taxol is used to treat ovarian, breast and non-small cell lung cancer.
Uploaded
February 15th, 2021
Embed
Share
Comments
There are no comments for Binding Of Taxol To A Tubulin Molecule. Click here to post the first comment.