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Glioblastoma brain cancer. Coloured 3D diffusion tensor imaging (DTI) magnetic resonance imaging (MRI) scan of nerve pathways (coloured) in a brain with a cancerous tumour (red, lower left) in the right temporoparietal region. The brain is seen from above, with the front of the brain at bottom. This cancer is a glioblastoma, the most common malignant primary brain tumour. Symptoms depend on the region of the brain affected, and include seizures, headaches, and memory and personality changes. Glioblastoma is particularly malignant. It arises from the supporting glial cells in the brain. Treatment is with a combination of surgery and radiotherapy, but the prognosis is poor. Death can occur within months. Diffusion tensor imaging (tractography) measures the direction of water diffusion, which in the brain reveals the orientation of nerve fibres.

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