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by Ramon Andrade 3dciencia/science Photo Library
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Illustration of a Taxol molecule. Taxol was first isolated from the bark of the Pacific yew tree (Taxus brevifolia) and is now made synthetically.... more
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Illustration of a Taxol molecule. Taxol was first isolated from the bark of the Pacific yew tree (Taxus brevifolia) and is now made synthetically. Taxol is an anti-cancer drug which stabilises microtubules in cells, disrupting their disassembly. This action results in chromosomes being unable to achieve a metaphase spindle configuration disrupting the progression of cell division (mitosis). Taxol can also prevent the microtubule detachment from centrosomes, a process normally activated during mitosis. Taxol is used to treat ovarian, breast and non-small cell lung cancer. Atoms are represented as spheres: carbon (green), oxygen (red) and nitrogen (blue).
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