Chimeric Antigen Receptor (car) Therapy #1
by Juan Gaertner/science Photo Library
Title
Chimeric Antigen Receptor (car) Therapy #1
Artist
Juan Gaertner/science Photo Library
Medium
Photograph - Photograph
Description
Illustration of engineered receptors (light blue) on the surface of a T-lymphocyte bind specifically to CD19-antigen molecules (red) on a leukemia cell. This activates a signal cascade in the T-cell leading to the segregation of vesicles that contain perforin and granzyme. The perforins build channels for the granzymes which enter the leukemia cell and activate finally the apoptosis (cell death) of the cancer cell.
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May 23rd, 2023
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