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Typhoid vaccination. First typhoid vaccination, photographed at the United States Army Medical School, Washington DC. Doctor Frederick Fuller Russell (right) vaccinating a volunteer, while doctor John Neate (centre right) fills a syringe. Typhoid is an infection of the digestive system caused by the bacteria Salmonella typhi. It is transmitted through infected food and water. It causes high fever, diarrhoea and a rash. Severe infections can include inflammation of the spleen and bones, delirium and erosion of the intestinal wall. Vaccinations involve exposing the body to dead or weakened disease-causing micro-organisms, strengthening the immune system against future infection.

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