Neuron In Alzheimer's Disease
by Thomas Deerinck, Ncmir/science Photo Library
Title
Neuron In Alzheimer's Disease
Artist
Thomas Deerinck, Ncmir/science Photo Library
Medium
Photograph - Photograph
Description
Neuron in Alzheimer's disease, coloured transmission electron micrograph (TEM). This neuron (nerve cell) contains a neurofibrillary tangle (pink) in the cytoplasm (green) of the cell. It consists of abnormal aggregates and insoluble fibres of the protein tau, and is known as a 'paired helical filament' (PHF). Tau protein is an abundant neural protein, aggregations of which are thought to play a role in Alzheimer's disease and other neural disorders. The cell nucleus (yellow) is at centre.
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September 23rd, 2018
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