False-col.sem Of Hybridoma Cell Producing Antibody
Dr Jeremy Burgess/science Photo Library
Photograph - Photograph
False-colour scanning electron micrograph of a hybridoma cell producing a monoclonal antibody to cytoskeleton protein. Monoclonal antibodies are produced by injecting a mouse with an antigen & harvesting its antibody response by removing the B lymphocytes. These are fused with myeloma (tumour) cells taken from a mutant lymphocyte source. The fusion product is called a hybridoma cell. B lymphocytes are short-lived; when fused with tumour cells, which divide indefinitely, the continuous production of antibody is secured. Hybridomas are screened for the required antibody;they are then cloned & produce that antibody. Magnification: x1500 at 35mm size.
September 21st, 2018
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