Muscle Myoblast Extracellular Matrix #2
by Dennis Kunkel Microscopy/science Photo Library
Title
Muscle Myoblast Extracellular Matrix #2
Artist
Dennis Kunkel Microscopy/science Photo Library
Medium
Photograph - Photograph
Description
Muscle myoblast (primitive embryonic muscle cell) secreting extracellular matrix (ECM), scanning electron micrograph (SEM). Skeletal muscle fibres are made when myoblasts fuse together. As a result muscle fibres have multiple nuclei. The ECMis a complex structural tissue component surrounding and supporting cells in mammalian tissues. The ECM is often referred to as the connective tissue. Many cells bind to components of the ECM. The cell to ECM adhesion is regulated by specific cell surface cellular adhesion molecules (CAM) known as integrins. The integrins transmit mechanical stimuli from the ECM to the cytoskeleton. Magnification: x1,200 when shortest axis printed at 25 millimetres.
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September 16th, 2018
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